Integrated regulation of L-type calcium channel Cav1.2 by miR-103 microRNA in neuropathic pain condition
نویسندگان
چکیده
منابع مشابه
Bidirectional integrative regulation of Cav1.2 calcium channel by microRNA miR-103: role in pain.
Chronic pain states are characterized by long-term sensitization of spinal cord neurons that relay nociceptive information to the brain. Among the mechanisms involved, up-regulation of Cav1.2-comprising L-type calcium channel (Cav1.2-LTC) in spinal dorsal horn have a crucial role in chronic neuropathic pain. Here, we address a mechanism of translational regulation of this calcium channel. Trans...
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ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2009
ISSN: 1662-453X
DOI: 10.3389/conf.neuro.01.2009.16.157